Description

5-(Methylsulfonyl)Picolinonitrile is a high-value, multi-functional heterocyclic building block and pharmaceutical intermediate. Its unique structure, featuring both a picolinonitrile core and a methylsulfonyl group, makes it a critical synthon for constructing complex molecules in medicinal chemistry and advanced material science. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its bioactive scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein functions.
• Custom Synthesis and Contract Manufacturing: A starting material for custom synthesis projects requiring functionalized pyridine derivatives.

Basic Information

Product Name	5-(Methylsulfonyl)Picolinonitrile
CAS No.	848141-13-9
Molecular Formula	C7H6N2O2S
Molecular Weight	182.20 g/mol
Synonyms	5-(Methylsulfonyl)-2-pyridinecarbonitrile; 2-Cyano-5-(methylsulfonyl)pyridine; 5-Methanesulfonylpyridine-2-carbonitrile; 5-Methylsulfonylpicolinonitrile; Pyridine, 2-cyano-5-(methylsulfonyl)-; 848141-13-9; 5-(Methylsulphonyl)picolinonitrile
EINECS	Contact for details

Quality Control

Our 5-(Methylsulfonyl)Picolinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.