Description

3-Chloro-4-(Pyridin-3-Ylmethoxy)Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its distinct aniline and pyridine functional groups. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop new drug candidates, leveraging its specific reactivity for constructing targeted molecular frameworks.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) and investigational new drugs.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in the development of specialty polymers, ligands for catalysis, and organic electronic materials.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing specialized azo dyes and high-performance pigments.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in academic and CRO/CMO settings.

Basic Information

Product Name	3-Chloro-4-(Pyridin-3-Ylmethoxy)Aniline
CAS No.	848134-24-7
Molecular Formula	C12H11ClN2O
Molecular Weight	234.68 g/mol
Synonyms	3-Chloro-4-[(pyridin-3-yl)methoxy]aniline; 3-Chloro-4-(3-pyridylmethoxy)aniline; 4-Amino-2-chloro-1-(3-pyridylmethoxy)benzene; 848134-24-7; Benzenamine, 3-chloro-4-[(3-pyridinyl)methoxy]-; 3-Pyridinemethanol, 4-amino-2-chloro-1-(3-pyridinylmethoxy)benzene
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(Pyridin-3-Ylmethoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) documenting full specifications are available upon request, supporting compliance with cGMP and ICH Q7 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.