Description

Ethyl 3-(Boc-Amino)-2,2-Difluoropropanoate is a high-value, protected amino acid derivative featuring a Boc-protected amine and a difluoro-substituted propanoate ester group. This compound serves as a critical chiral building block in advanced organic synthesis, enabling the precise introduction of fluorinated amino acid motifs. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including peptide mimetics and protease inhibitors.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated amino acids and peptides used in drug discovery programs.
• Protease Inhibitor Development: Used in the research and synthesis of potential inhibitors targeting various enzymes.
• Agrochemical Synthesis: Serves as a building block for creating novel fluorinated active ingredients with enhanced properties.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by incorporating difluoro motifs into lead compounds.
• Peptidomimetics: Facilitates the creation of metabolically stable peptide analogs for therapeutic applications.
• Chemical Biology Probes: Used in the development of labeled compounds and probes for studying biological mechanisms.

Basic Information

Product Name	Ethyl 3-(Boc-Amino)-2,2-Difluoropropanoate
CAS No.	847986-13-4
Molecular Formula	C₁₀H₁₇F₂NO₄
Molecular Weight	253.24 g/mol
Synonyms	Ethyl 3-[(tert-Butoxycarbonyl)amino]-2,2-difluoropropanoate; 2,2-Difluoro-3-[(tert-butoxycarbonyl)amino]propanoic Acid Ethyl Ester; Boc-NH-CH(CF₂)-COOEt; tert-Butyl N-(2,2-difluoro-3-ethoxy-3-oxopropyl)carbamate; 3-(Boc-Amino)-2,2-difluoropropionic Acid Ethyl Ester; N-Boc-2,2-difluoro-β-alanine Ethyl Ester; Ethyl 3-Amino-2,2-difluoropropanoate, N-Boc Protected
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Boc-Amino)-2,2-Difluoropropanoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.