Description

tert-Butyl 5-Hydroxynicotinate is a high-purity chemical intermediate, specifically a protected derivative of 5-hydroxynicotinic acid. This compound is valued for its role as a versatile building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for API synthesis and advanced material creation.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the nicotinate core structure.
• Fine Chemical Production: Serves as a precursor for the manufacture of specialty chemicals, dyes, and functional materials.
• Research & Development: Employed in academic and industrial R&D labs for medicinal chemistry and process chemistry studies.
• Ligand and Catalyst Preparation: Useful for constructing complex organic ligands used in catalytic systems.

Basic Information

Product Name	tert-Butyl 5-Hydroxynicotinate
CAS No.	847943-53-7
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	5-Hydroxynicotinic Acid tert-Butyl Ester; tert-Butyl 5-Hydroxypyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-hydroxy-, 1,1-dimethylethyl ester; 5-(tert-Butoxycarbonyl)pyridin-3-ol; Nicotinic acid, 5-hydroxy-, tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Hydroxynicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We are committed to meeting the stringent requirements of cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.