Description

5-Fluoro-2-Nitropyridin-3-Ol is a high-value fluorinated nitropyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both electron-withdrawing nitro and fluoro substituents adjacent to a hydroxyl group, makes it a versatile building block for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides that leverage the biological activity of fluorinated pyridine scaffolds.
• Material Science Research: Used in the creation of advanced organic materials, including liquid crystals, organic semiconductors, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Serves as a reactive handle for bioconjugation and the development of chemical probes and enzyme inhibitors.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the nitropyridine core contributes to color and stability properties.
• Academic & R&D Laboratories: Fundamental reagent for methodological development in organic synthesis, including cross-coupling and nucleophilic substitution reactions.

Basic Information

Product Name	5-Fluoro-2-Nitropyridin-3-Ol
CAS No.	847902-56-1
Molecular Formula	C5H3FN2O3
Molecular Weight	158.09 g/mol
Synonyms	3-Hydroxy-5-fluoro-2-nitropyridine; 5-Fluoro-3-hydroxy-2-nitropyridine; 2-Nitro-5-fluoro-3-pyridinol; 5-Fluoro-2-nitro-3-pyridinol; 847902-56-1; 3-Pyridinol, 5-fluoro-2-nitro-; 5-Fluoro-2-nitropyridin-3-ol
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-2-Nitropyridin-3-Ol is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical applications. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is available for each lot, detailing all specifications and test results. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical and industrial intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.