Description

2-Oxabicyclo[2.2.2]Oct-7-Ene-6-Carboxylicacid,4-Fluoro-3-Oxo-,Methylester,(1R,4S,6S)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic lactone derivative, serving as a critical chiral building block and synthetic intermediate. Its value lies in its complex, rigid molecular framework and the presence of reactive functional groups, enabling precise chemical transformations for advanced synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries who require sophisticated intermediates for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a precursor or scaffold in catalytic asymmetric reactions to construct complex, enantiomerically pure molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization due to its unique bicyclic structure and fluorine substituent.
• Process Chemistry Development: Serves as a starting material or advanced intermediate in the scale-up and optimization of synthetic routes for target molecules.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical fidelity.
• Academic & Industrial R&D: A valuable compound for methodological development in organic synthesis and exploring new reaction pathways.

Basic Information

Product Name	2-Oxabicyclo[2.2.2]Oct-7-Ene-6-Carboxylicacid,4-Fluoro-3-Oxo-,Methylester,(1R,4S,6S)-Rel-(9Ci)
CAS No.	847823-48-7
Molecular Formula	C9H9FO4
Molecular Weight	200.16 g/mol
Synonyms	(1R,4S,6S)-rel-4-Fluoro-3-oxo-2-oxabicyclo[2.2.2]oct-7-ene-6-carboxylic acid methyl ester; Methyl (1R,4S,6S)-rel-4-fluoro-3-oxo-2-oxabicyclo[2.2.2]oct-7-ene-6-carboxylate; 4-Fluoro-3-oxo-2-oxabicyclo[2.2.2]oct-7-ene-6-carboxylic acid methyl ester, (1R,4S,6S)-rel-; Bicyclic Fluorinated Lactone Ester; 847823-48-7; (rel)-(1R,4S,6S)-Methyl 4-fluoro-3-oxo-2-oxabicyclo[2.2.2]oct-7-ene-6-carboxylate
EINECS	Contact for details

Quality Control

Our production of 2-Oxabicyclo[2.2.2]Oct-7-Ene-6-Carboxylicacid,4-Fluoro-3-Oxo-,Methylester,(1R,4S,6S)-Rel-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. All materials undergo rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry, to confirm identity, stereochemical purity, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.