Description

1,8-Naphthyridin-2(1H)-One, 3-Amino-3,4-Dihydro- is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 847684-77-9. This heterocyclic compound is a critical building block in modern medicinal chemistry, valued for its unique fused-ring structure that serves as a core scaffold for bioactive molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the areas of oncology and anti-infective drugs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, especially those targeting kinase inhibition.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic synthesis to construct novel naphthyridine-based heterocycles.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection products.
• Material Science: Investigated as a ligand or functional component in the creation of advanced organic electronic materials.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for methodological studies and discovery chemistry.

Basic Information

Product Name	1,8-Naphthyridin-2(1H)-One, 3-Amino-3,4-Dihydro-
CAS No.	847684-77-9
Molecular Formula	C8H9N3O
Molecular Weight	163.18 g/mol
Synonyms	3-Amino-1,2,3,4-tetrahydro-1,8-naphthyridin-2-one; 3-Amino-3,4-dihydro-1,8-naphthyridin-2(1H)-one; 3-Amino-1,2,3,4-tetrahydro-[1,8]naphthyridin-2-one; 3-Amino-3,4-dihydro-2H-[1,8]naphthyridin-2-one; 2(1H)-1,8-Naphthyridinone, 3-amino-3,4-dihydro-; 847684-77-9; 3-Amino-1,2,3,4-tetrahydro-1,8-naphthyridin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridin-2(1H)-One, 3-Amino-3,4-Dihydro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.