Description

(3E)-1-(1H-Imidazol-1-Yl)-4-Phenyl-2-Pyridin-4-Ylbut-3-En-2-Ol is a high-purity, advanced pharmaceutical intermediate of significant interest in modern medicinal chemistry. This compound matters for its role as a sophisticated building block in the synthesis of targeted therapeutic agents, offering precise structural control for drug discovery programs. It is primarily needed by R&D teams and process chemists in the pharmaceutical and biotechnology industries working on novel small-molecule drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or building block for constructing compound libraries in structure-activity relationship (SAR) studies.
• Kinase Inhibitor Synthesis: Potential intermediate in the synthesis of compounds targeting specific kinase pathways, given its imidazole and pyridine motifs.
• Biochemical Tool Compound: Serves as a research chemical for probing biological mechanisms and validating novel drug targets in vitro.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale manufacturing of complex drug molecules.

Basic Information

Product Name	(3E)-1-(1H-Imidazol-1-Yl)-4-Phenyl-2-Pyridin-4-Ylbut-3-En-2-Ol
CAS No.	847670-79-5
Molecular Formula	C22H19N3O
Molecular Weight	341.41 g/mol
Synonyms	1-(1H-Imidazol-1-yl)-4-phenyl-2-(4-pyridinyl)-3-buten-2-ol, (E)-1-(1H-Imidazol-1-yl)-4-phenyl-2-(pyridin-4-yl)but-3-en-2-ol, 4-Phenyl-2-(4-pyridyl)-1-(imidazol-1-yl)-3-buten-2-ol, (3E)-1-(1H-Imidazol-1-yl)-4-phenyl-2-(4-pyridinyl)-3-buten-2-ol, 847670-79-5, But-3-en-2-ol, 1-(1H-imidazol-1-yl)-4-phenyl-2-(4-pyridinyl)-, (3E)-
EINECS	Contact for details

Quality Control

Our (3E)-1-(1H-Imidazol-1-Yl)-4-Phenyl-2-Pyridin-4-Ylbut-3-En-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.