Description

(E)-4-(2,4-Dichloro-Phenyl)-1-Imidazol-1-Yl-2-Pyridin-3-Yl-But-3-En-2-Ol CAS NO 847670-73-9 is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and complex heterocyclic structure. This compound is of critical importance for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential new drug candidates, especially in oncology and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• API Development: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Biochemical Tool Compound: Utilized in vitro and in vivo to study and validate novel biological targets and mechanisms of action.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of specialized, non-commercial compounds for client research programs.

Basic Information

Product Name	(E)-4-(2,4-Dichloro-Phenyl)-1-Imidazol-1-Yl-2-Pyridin-3-Yl-But-3-En-2-Ol
CAS No.	847670-73-9
Molecular Formula	C22H17Cl2N3O
Molecular Weight	410.30 g/mol
Synonyms	(E)-4-(2,4-Dichlorophenyl)-1-(1H-imidazol-1-yl)-2-(pyridin-3-yl)but-3-en-2-ol; 4-(2,4-Dichlorophenyl)-1-imidazol-1-yl-2-(3-pyridinyl)-3-buten-2-ol, (E)-; (E)-4-(2,4-Dichlorophenyl)-1-(imidazol-1-yl)-2-(pyridin-3-yl)but-3-en-2-ol; CAS 847670-73-9; SCHEMBL10806227; AKOS025247317; ZINC000253930715; But-3-en-2-ol, 4-(2,4-dichlorophenyl)-1-imidazol-1-yl-2-(3-pyridinyl)-, (E)-
EINECS	Contact for details

Quality Control

Our production of (E)-4-(2,4-Dichloro-Phenyl)-1-Imidazol-1-Yl-2-Pyridin-3-Yl-But-3-En-2-Ol adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and physical characteristics is provided with each shipment to guarantee traceability and consistency for your critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); therefore, the container must be kept tightly sealed under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.