Description

(3E)-4-(4-Chlorophenyl)-1-(1H-Imidazol-1-Yl)-2-Pyridin-3-Ylbut-3-En-2-Ol CAS NO 847670-71-7 is a high-purity, non-racemic chiral compound featuring a complex molecular architecture combining imidazole, pyridine, and chlorophenyl pharmacophores. This compound is of significant value as a sophisticated pharmaceutical intermediate and a versatile research chemical for medicinal chemistry programs. It is primarily sought by R&D teams in the pharmaceutical, agrochemical, and fine chemical sectors for the development of new active ingredients targeting a range of biological pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology, antifungal, and CNS therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and library synthesis.
• Agrochemical Development: Serves as an intermediate in the research and production of advanced crop protection agents and pesticides.
• Biochemical Tool Compound: Utilized in biochemical assays and as a probe to study enzyme inhibition or receptor modulation.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes for producing complex, high-value specialty chemicals.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	(3E)-4-(4-Chlorophenyl)-1-(1H-Imidazol-1-Yl)-2-Pyridin-3-Ylbut-3-En-2-Ol
CAS No.	847670-71-7
Molecular Formula	C18H16ClN3O
Molecular Weight	325.79 g/mol
Synonyms	(3E)-4-(4-Chlorophenyl)-1-(1H-imidazol-1-yl)-2-(pyridin-3-yl)but-3-en-2-ol; 4-(4-Chlorophenyl)-1-(imidazol-1-yl)-2-(3-pyridinyl)-3-buten-2-ol (E)-; 3-Buten-2-ol, 4-(4-chlorophenyl)-1-(1H-imidazol-1-yl)-2-(3-pyridinyl)-, (3E)-; CAS 847670-71-7; (E)-4-(4-Chlorophenyl)-1-(1H-imidazol-1-yl)-2-(pyridin-3-yl)but-3-en-2-ol
EINECS	Contact for details

Quality Control

Our production of (3E)-4-(4-Chlorophenyl)-1-(1H-Imidazol-1-Yl)-2-Pyridin-3-Ylbut-3-En-2-Ol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and chiral integrity. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and regulatory compliance (REACH, FDA DMF where applicable) ensures material suitable for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specified enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.