Description

2,5-Dichloro-4-Hydroxypyridine is a halogenated pyridine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in antiviral, antibacterial, and anticancer research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and inhibitors to study biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trials.

Basic Information

Item	Detail
Product Name	2,5-Dichloro-4-Hydroxypyridine
CAS No.	847664-65-7
Molecular Formula	C5H3Cl2NO
Molecular Weight	163.99 g/mol
Synonyms	4-Hydroxy-2,5-dichloropyridine; 2,5-Dichloro-4-pyridinol; 2,5-Dichloro-4(1H)-pyridinone; 4-Pyridinol, 2,5-dichloro-; 2,5-Dichloro-4-hydroxypyridine; 2,5-Dichloro-4-pyridone
EINECS	Contact for details

Quality Control

Our 2,5-Dichloro-4-Hydroxypyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of our global clientele in regulated industries. Certificates of Analysis (COA) detailing all specifications are provided with every shipment, and we support audits and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.