Description

3-Chloro-5-(Chloromethyl)Pyridine Hydrochloride is a high-purity, versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional reactivity, featuring both a chloromethyl group and a halogenated aromatic ring, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of functionalized polymers and organic electronic materials due to its reactive sites.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Bioconjugation and Probe Development: Useful in life sciences for creating molecular probes and bioconjugates via its reactive chloromethyl handle.

Basic Information

Product Name	3-Chloro-5-(Chloromethyl)Pyridine Hydrochloride
CAS No.	847610-86-0
Molecular Formula	C6H6Cl2N • HCl
Molecular Weight	212.48 g/mol (Free base: 176.02 g/mol)
Synonyms	5-(Chloromethyl)-3-chloropyridine hydrochloride; 3-Chloro-5-chloromethylpyridine HCl; 3-Chloro-5-(chloromethyl)pyridinium chloride; Pyridine, 3-chloro-5-(chloromethyl)-, hydrochloride; (3-Chloro-5-pyridinyl)methyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-(Chloromethyl)Pyridine Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.