Description

4-(3-Nitropyridin-2-Yl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific nitropyridine-substituted benzoic acid structure. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and process optimization.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of target drug molecules, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a structural component in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic architecture.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex polycyclic or functionalized aromatic systems via coupling and condensation reactions.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed reactions due to the potential coordination sites on the pyridine and carboxylic acid groups.
• Material Science Precursor: Can be utilized in the synthesis of organic semiconductors, dyes, or photoactive materials for advanced electronic applications.

Basic Information

Product Name	4-(3-Nitropyridin-2-Yl)Benzoic Acid
CAS No.	847446-89-3
Molecular Formula	C12H8N2O4
Molecular Weight	244.20 g/mol
Synonyms	2-(4-Carboxyphenyl)-3-nitropyridine; 4-(3-Nitro-2-pyridinyl)benzoic Acid; Benzoic acid, 4-(3-nitro-2-pyridinyl)-; 3-Nitro-2-(4-carboxyphenyl)pyridine; 847446-89-3; 4-(3-Nitropyridin-2-yl)benzoic acid; 4-(3-Nitro-2-pyridyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-(3-Nitropyridin-2-Yl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.