Description

(S)-tert-Butyl 4-((S)-4-Benzyl-2-Oxooxazolidin-3-Yl)-3-Methyl-4-Oxobutanoate is a high-purity chiral building block and advanced pharmaceutical intermediate of significant synthetic utility. This compound is valued for its role in the stereoselective synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the production of enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents, including protease inhibitors and other biologically active molecules.
• Asymmetric Synthesis: Utilized as an auxiliary or precursor in stereocontrolled carbon-carbon and carbon-heteroatom bond-forming reactions.
• Peptidomimetic Research: Serves as a crucial component in the design and synthesis of peptide analogs and mimetics for drug discovery programs.
• Agrochemical Development: Employed in the research and production of enantiomerically pure pesticides and herbicides.
• Academic & Process Chemistry: Used in methodological development and scale-up studies for new synthetic routes requiring high stereochemical fidelity.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	(S)-tert-Butyl 4-((S)-4-Benzyl-2-Oxooxazolidin-3-Yl)-3-Methyl-4-Oxobutanoate
CAS No.	847406-37-5
Molecular Formula	C19H25NO5
Molecular Weight	347.41 g/mol
Synonyms	(S)-tert-Butyl 4-((S)-4-benzyl-2-oxooxazolidin-3-yl)-3-methyl-4-oxobutanoate; (S)-tert-Butyl 3-methyl-4-oxo-4-[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]butanoate; (S)-tert-Butyl 4-((S)-4-benzyl-2-oxooxazolidin-3-yl)-3-methyl-4-oxobutyrate; (S)-tert-Butyl 4-[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-3-methyl-4-oxobutanoate; tert-Butyl (S)-4-((S)-4-benzyl-2-oxooxazolidin-3-yl)-3-methyl-4-oxobutanoate; Evans Auxiliary Derivative; Butanoic acid, 4-[(4S)-4-benzyl-2-oxo-3-oxazolidinyl]-3-methyl-4-oxo-, 1,1-dimethylethyl ester, (3S)-
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 4-((S)-4-Benzyl-2-Oxooxazolidin-3-Yl)-3-Methyl-4-Oxobutanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.