Description

Cy7.5 CAS NO 847180-48-7 is a near-infrared (NIR) cyanine dye belonging to the heptamethine indocyanine family, characterized by its strong absorption and fluorescence emission in the NIR region. This compound is critical for advanced bioimaging and diagnostic applications due to its deep tissue penetration and minimal background autofluorescence. It is primarily needed by researchers and manufacturers in the biotechnology, pharmaceutical, and medical diagnostics sectors for applications such as in vivo imaging, flow cytometry, and the development of fluorescent probes and conjugates.

Application

• In Vivo Imaging Agent: Used as a fluorescent tag for non-invasive deep-tissue imaging in preclinical animal studies.
• Flow Cytometry & Cell Sorting: Serves as a vital stain for detecting and isolating specific cell populations in complex biological samples.
• Fluorescent Probe & Conjugate Synthesis: Acts as a reactive intermediate for labeling antibodies, peptides, nanoparticles, and other biomolecules.
• Optical Sensor Development: Incorporated into materials for creating sensors that detect biological analytes or environmental changes.
• Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizer for targeted cancer treatments.
• DNA/Protein Labeling & Detection: Utilized in gel electrophoresis, blotting, and microarray technologies for sensitive biomolecule detection.

Basic Information

Product Name	Cy7.5
CAS No.	847180-48-7
Molecular Formula	C47H55ClN2O6S2
Molecular Weight	851.53 g/mol
Synonyms	Cy7.5 dye; Cyanine7.5; Sulfo-Cyanine7.5; 2-[7-[1,3-Dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benz[e]indolium hydroxide, inner salt; IR-1061 derivative; NIR-797 analog; Heptamethine cyanine dye; Near-infrared fluorescent dye
EINECS	Contact for details

Quality Control

Our Cy7.5 is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectrophotometry for absorbance/fluorescence verification, and NMR for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant (e.g., in a sealed bag with silica gel) to minimize degradation. For long-term stability, store under an inert atmosphere (argon or nitrogen). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Dark green to blue-green solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95.0%
Absorption Maximum (λmax)	788 ± 5 nm
Emission Maximum	808 ± 5 nm
Extinction Coefficient (ε)	≥ 200,000 cm⁻¹M⁻¹
Moisture Content (KF)	≤ 5.0 %
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.