Description

4-Amino-3-Methyl-Pyrazole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected pyrazole derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and pharmaceutical development, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the pyrazole core's bioactivity.
• Chemical Biology: Serves as a versatile scaffold for designing molecular probes and enzyme inhibitors.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Material Science: Potential precursor for the development of specialty polymers and functional materials.

Basic Information

Product Name	4-Amino-3-Methyl-Pyrazole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	847139-23-5
Molecular Formula	C9H15N3O2
Molecular Weight	197.24 g/mol
Synonyms	tert-Butyl 4-Amino-3-methyl-1H-pyrazole-1-carboxylate; 4-Amino-3-methyl-1H-pyrazole-1-carboxylic acid tert-butyl ester; 1-Boc-4-amino-3-methylpyrazole; 3-Methyl-4-aminopyrazole-1-carboxylic acid tert-butyl ester; 4-Amino-3-methylpyrazole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-amino-3-methylpyrazole; Boc-4-Amino-3-methylpyrazole
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Methyl-Pyrazole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.