Description

5-Amino-4-Bromo-2-Chloro-6-Methyl-Nicotinonitrile is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated and amino-substituted pyridine core makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive pyridine scaffold.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Advanced Material Development: A building block for organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	5-Amino-4-Bromo-2-Chloro-6-Methyl-Nicotinonitrile
CAS No.	847060-24-6
Molecular Formula	C7H5BrClN3
Molecular Weight	246.49 g/mol
Synonyms	4-Bromo-2-chloro-6-methyl-5-aminonicotinonitrile; 5-Amino-4-bromo-2-chloro-6-methylpyridine-3-carbonitrile; 3-Cyano-5-amino-4-bromo-2-chloro-6-methylpyridine; 847060-24-6; 4-Bromo-2-chloro-5-cyano-6-methyl-3-pyridinamine
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-4-Bromo-2-Chloro-6-Methyl-Nicotinonitrile is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and other relevant spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.