Description

2-Hydroxy-6-(Cyclopropyl)Pyridine is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a phenolic hydroxyl group and a cyclopropyl substituent on the pyridine ring, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a crucial building block in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and cyclopropane motifs.
• Ligand Precursor in Catalysis: Used to synthesize specialized nitrogen-oxygen (N,O) bidentate ligands for transition metal catalysis, enabling asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its potential for coordination and functionalization.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	2-Hydroxy-6-(Cyclopropyl)Pyridine
CAS No.	846551-99-3
Molecular Formula	C8H9NO
Molecular Weight	135.16 g/mol
Synonyms	6-Cyclopropylpyridin-2-ol; 2-Pyridinol, 6-cyclopropyl-; 6-Cyclopropyl-2-hydroxypyridine; 6-Cyclopropyl-2-pyridinol; 2-Hydroxy-6-cyclopropylpyridine; 6-Cyclopropyl-2(1H)-pyridinone (tautomer)
EINECS	Contact for details

Quality Control

Every batch of 2-Hydroxy-6-(Cyclopropyl)Pyridine is produced under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.