Description

2-Bromo-5-(Difluoromethoxy)Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and difluoromethoxy substituents, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, such as herbicides and fungicides, where the difluoromethoxy group can enhance biological activity and metabolic stability.
• Material Science Research: Acts as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form new carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and diagnostic agents for biochemical research.

Basic Information

Product Name	2-Bromo-5-(Difluoromethoxy)Pyridine
CAS No.	845827-14-7
Molecular Formula	C6H4BrF2NO
Molecular Weight	224.00 g/mol
Synonyms	5-(Difluoromethoxy)-2-bromopyridine; 2-Bromo-5-difluoromethoxypyridine; Pyridine, 2-bromo-5-(difluoromethoxy)-; 845827-14-7
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Difluoromethoxy)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.