Description

5-(4-Fluorophenyl)Pyridine-2-Carboxylic Acid is a high-purity fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its structural motif, which is integral to developing molecules with targeted biological and physical properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and insecticides, where the fluorophenyl-pyridine core can enhance bioavailability and environmental stability.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs), leveraging its carboxylic acid functionality for coordination.
• Material Science: Acts as a monomer or functional additive in the production of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in regulatory and analytical laboratories.

Basic Information

Product Name	5-(4-Fluorophenyl)Pyridine-2-Carboxylic Acid
CAS No.	845826-99-5
Molecular Formula	C₁₂H₈FNO₂
Molecular Weight	217.20 g/mol
Synonyms	2-Pyridinecarboxylic acid, 5-(4-fluorophenyl)-; 5-(4-Fluorophenyl)picolinic acid; 5-(p-Fluorophenyl)picolinic acid; 5-(4-Fluorophenyl)-2-pyridinecarboxylic acid; 845826-99-5; 5-(4-Fluorophenyl)pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 5-(4-Fluorophenyl)Pyridine-2-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.