Description

4-(6-(Trifluoromethyl)Pyridin-3-Yl)Benzoic Acid is a high-value trifluoromethylpyridine-substituted benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a pyridine ring and a carboxylic acid group, makes it an essential intermediate for creating compounds with tailored electronic and steric properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients, as well as by manufacturers of specialty materials and liquid crystal compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, such as herbicides and fungicides, where the trifluoromethylpyridine moiety can enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystal compounds for display technologies, contributing to improved dielectric anisotropy and thermal stability.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials for applications in OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for constructing complex heterocyclic systems and exploring structure-activity relationships.
• Coordination Chemistry Ligand: The carboxylic acid and pyridine nitrogen can act as donor sites for metal coordination, useful in catalyst design and metal-organic framework (MOF) synthesis.

Basic Information

Product Name	4-(6-(Trifluoromethyl)Pyridin-3-Yl)Benzoic Acid
CAS No.	845826-95-1
Molecular Formula	C13H8F3NO2
Molecular Weight	267.20 g/mol
Synonyms	[4-(6-(Trifluoromethyl)pyridin-3-yl)]benzoic acid; 4-[6-(Trifluoromethyl)-3-pyridinyl]benzoic Acid; Benzoic acid, 4-[6-(trifluoromethyl)-3-pyridinyl]-; 4-(6-(Trifluoromethyl)-3-pyridyl)benzoic acid; 4-(6-Trifluoromethylpyridin-3-yl)benzoic acid; 3-Pyridinecarboxylic acid, 6-(trifluoromethyl)-, 4-phenyl ester (related); 845826-95-1
EINECS	Contact for details

Quality Control

Our 4-(6-(Trifluoromethyl)Pyridin-3-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.