Description

1-(Trimethylsilyl)-3-iso-Propoxybenzene is a specialized organosilicon compound featuring a silyl-protected phenol moiety, serving as a versatile building block in advanced organic synthesis. Its value lies in its dual functionality, offering both a silyl protecting group and an isopropoxy substituent, which are critical for controlling reactivity and selectivity in complex molecular constructions. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, particularly those requiring phenol protection/deprotection strategies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the silyl group aids in stepwise synthesis.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of silicon-containing polymers, resins, and advanced organic electronic materials.
• Chemical Derivatization: Useful for modifying other compounds to introduce the trimethylsilyl group for analytical purposes or to alter physical properties.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new reaction pathways in organic chemistry laboratories.

Basic Information

Product Name	1-(Trimethylsilyl)-3-iso-Propoxybenzene
CAS No.	845823-21-4
Molecular Formula	C12H20OSi
Molecular Weight	208.37 g/mol
Synonyms	3-Isopropoxy-1-(trimethylsilyl)benzene; m-Isopropoxytrimethylsilylbenzene; 1-Isopropoxy-3-(trimethylsilyl)benzene; Benzene, 1-(trimethylsilyl)-3-(1-methylethoxy)-; (3-Isopropoxyphenyl)trimethylsilane; TMS-Protected 3-Isopropoxybenzene; Trimethyl(3-isopropoxyphenyl)silane
EINECS	Contact for details

Quality Control

Our 1-(Trimethylsilyl)-3-iso-Propoxybenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and process chemistry. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and purity. A Certificate of Analysis (COA) detailing specific lot results is provided with every shipment, and our quality system supports compliance with cGMP and ISO standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.