Description

1-(Trimethylsilyl)-3,5-Dimethyl-4-Methoxybenzene is a specialized organosilicon compound, CAS NO 845823-17-8, valued for its role as a versatile protecting group and intermediate in advanced synthetic chemistry. Its unique structure provides steric bulk and stability, making it crucial for constructing complex molecules where selective functionalization is required. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for protecting sensitive hydroxyl groups during multi-step reactions.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where its silicon moiety modifies compound activity and stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers, silicones, and advanced organic electronic materials.
• Organic Synthesis Reagent: Employed as a silylating agent in laboratory and industrial-scale organic synthesis to introduce the trimethylsilyl (TMS) protecting group.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists exploring new synthetic routes and novel compound libraries.
• Fine Chemical Production: Intermediate in the manufacture of complex fragrances, flavors, and dyes requiring specific, protected aromatic systems.

Basic Information

Product Name	1-(Trimethylsilyl)-3,5-Dimethyl-4-Methoxybenzene
CAS No.	845823-17-8
Molecular Formula	C₁₂H₂₀OSi
Molecular Weight	208.37 g/mol
Synonyms	4-Methoxy-3,5-dimethylphenyltrimethylsilane; Trimethyl(4-methoxy-3,5-dimethylphenyl)silane; 3,5-Dimethyl-4-methoxyphenyltrimethylsilane; TMS-protected 3,5-dimethyl-4-methoxyphenol; 1-Trimethylsilyl-3,5-dimethyl-4-methoxybenzene; (4-Methoxy-3,5-dimethylphenyl)(trimethyl)silane
EINECS	Contact for details

Quality Control

Our 1-(Trimethylsilyl)-3,5-Dimethyl-4-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.