Description

5-Bromo-2-(Piperidin-4-yl)pyridine is a versatile and high-value heterocyclic building block of significant interest in modern organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on drug discovery programs, especially those targeting central nervous system (CNS) disorders and other therapeutic areas where the piperidine-pyridine scaffold is pharmacologically relevant.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and candidate molecules for drug discovery.
• Kinase Inhibitor Development: Used in the construction of small-molecule kinase inhibitors, a major class of targeted cancer therapies.
• CNS Drug Research: Serves as a building block for compounds targeting neurological receptors and enzymes.
• Agrochemical Synthesis: Employed in the development of novel herbicides and fungicides.
• Ligand Synthesis for Catalysis: Useful for creating sophisticated nitrogen-containing ligands used in asymmetric catalysis.
• Chemical Biology Probes: Incorporated into tool compounds for studying biological pathways and protein function.
• Material Science Research: Potential monomer or precursor for functionalized polymers and advanced materials.

Basic Information

Product Name	5-Bromo-2-(Piperidin-4-yl)pyridine
CAS No.	845788-60-5
Molecular Formula	C10H13BrN2
Molecular Weight	241.13 g/mol
Synonyms	5-Bromo-2-(4-piperidinyl)pyridine; 2-(4-Piperidinyl)-5-bromopyridine; 5-Bromo-2-piperidin-4-ylpyridine; 4-(5-Bromopyridin-2-yl)piperidine; 845788-60-5; 5-Bromo-2-(piperidin-4-yl)pyridine; 5-Bromo-2-(4-piperidyl)pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Piperidin-4-yl)pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.