Description

6-Ethynyl-2-Pyridinemethanol CAS NO 845658-76-6 is a high-value pyridine derivative building block featuring both an ethynyl group and a hydroxymethyl substituent, enabling versatile chemical transformations. This compound is critical for the synthesis of complex molecules in advanced research and development, particularly in pharmaceutical chemistry. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other targeted therapy research.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand Synthesis: Serves as a precursor for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the development of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Utilized in click chemistry and bio-conjugation strategies to create molecular probes for studying biological systems.
• Academic & Contract Research: Essential reagent for synthetic organic chemistry research in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	6-Ethynyl-2-Pyridinemethanol
CAS No.	845658-76-6
Molecular Formula	C8H7NO
Molecular Weight	133.15 g/mol
Synonyms	2-(Hydroxymethyl)-6-ethynylpyridine; (6-Ethynyl-2-pyridinyl)methanol; 6-Ethynyl-2-pyridylmethanol; 2-Pyridinemethanol, 6-ethynyl-; 6-Ethynylpyridine-2-methanol
EINECS	Contact for details

Quality Control

Our 6-Ethynyl-2-Pyridinemethanol is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding R&D and scale-up applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool (15-25°C), dry place. Due to its hygroscopic and easily oxidized nature, the container should be opened only under controlled, moisture-free conditions and resealed immediately after use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.