Description

5-Oxo-1-(Pyridin-2-Ylmethyl)Pyrrolidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct pyrrolidone core functionalized with a pyridinylmethyl group. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug discovery. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of novel drug candidates targeting neurological and inflammatory pathways.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic molecules due to its reactive carboxylic acid and lactam functionalities.
• Chemical Research & Development: Serves as a reference standard and starting material in academic and industrial R&D labs for method development and compound library synthesis.
• Pre-clinical Drug Development: Employed in the synthesis of compounds for pharmacological screening, pharmacokinetic studies, and toxicity assessments.

Basic Information

Product Name	5-Oxo-1-(Pyridin-2-Ylmethyl)Pyrrolidine-3-Carboxylic Acid
CAS No.	845546-25-0
Molecular Formula	C12H14N2O3
Molecular Weight	234.25 g/mol
Synonyms	1-[(Pyridin-2-yl)methyl]-5-oxopyrrolidine-3-carboxylic acid; 5-Oxo-1-(2-pyridylmethyl)pyrrolidine-3-carboxylic acid; 3-Pyrrolidinecarboxylic acid, 1-(2-pyridinylmethyl)-5-oxo-; 1-(Pyridin-2-ylmethyl)pyrrolidine-3-carboxylic acid 5-oxide; 845546-25-0; UNII-9C5K3R4WQH
EINECS	Contact for details

Quality Control

Our 5-Oxo-1-(Pyridin-2-Ylmethyl)Pyrrolidine-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for each shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.