Description

5-Oct-1-Ynylnicotinic Acid is a specialized organic building block featuring a unique alkyne-substituted nicotinic acid structure. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in click chemistry and cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new crop protection agents and herbicides due to its reactive alkyne moiety.
• Material Science: Acts as a monomer or functionalizing agent in the creation of advanced polymers and specialty materials.
• Click Chemistry: An ideal substrate for Huisgen 1,3-dipolar cycloaddition reactions to create triazole-linked compounds.
• Cross-Coupling Reactions: Utilized in Sonogashira, Heck, and other palladium-catalyzed coupling reactions to construct complex molecular architectures.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Oct-1-Ynylnicotinic Acid
CAS No.	845266-29-7
Molecular Formula	C14H15NO2
Molecular Weight	229.27 g/mol
Synonyms	5-(Oct-1-yn-1-yl)nicotinic acid; 3-Pyridinecarboxylic acid, 5-(1-octyn-1-yl)-; Nicotinic acid, 5-oct-1-ynyl-; 5-(1-Octynyl)nicotinic acid
EINECS	Contact for details

Quality Control

Our 5-Oct-1-Ynylnicotinic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.