Description

2-([5-(Trifluoromethyl)-2-Pyridyl]Sulfonyl)Acetonitrile is a high-value, specialized organic intermediate featuring a pyridine core substituted with a trifluoromethyl group and a sulfonylacetonitrile moiety. This compound is critical for its role in advanced synthetic chemistry, particularly in the construction of complex molecules for pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethylpyridine scaffold.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	2-([5-(Trifluoromethyl)-2-Pyridyl]Sulfonyl)Acetonitrile
CAS No.	845266-24-2
Molecular Formula	C8H5F3N2O2S
Molecular Weight	250.20 g/mol
Synonyms	2-((5-(Trifluoromethyl)pyridin-2-yl)sulfonyl)acetonitrile; Acetonitrile, 2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]-; 2-Pyridinesulfonylacetonitrile, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-2-pyridylsulfonylacetonitrile; 2-((5-Trifluoromethyl-2-pyridyl)sulfonyl)acetonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-([5-(Trifluoromethyl)-2-Pyridyl]Sulfonyl)Acetonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.