Description

Atacicept is a recombinant fusion protein designed to inhibit B-cell stimulating factors. This targeted biologic agent is significant for its role in modulating specific pathways of the immune system. It is primarily required by pharmaceutical research and development organizations focused on autoimmune and inflammatory diseases.

Application

• Biopharmaceutical Research: A key reagent in preclinical studies investigating B-cell mediated autoimmune disorders.
• Drug Discovery & Development: Used as a reference standard and active pharmaceutical ingredient (API) in the development of novel immunomodulatory therapies.
• Mechanistic Studies: Employed in vitro and in vivo to study the BLyS and APRIL signaling pathways and their role in disease pathology.
• Clinical Trial Material: Serves as a critical component in the manufacturing of materials for clinical-stage investigations.

Basic Information

Product Name	Atacicept
CAS No.	845264-92-8
Molecular Formula	C2150H3318N562O668S16
Molecular Weight	~48.8 kDa
Synonyms	TACI-Ig; Atacicept recombinant; Transmembrane activator and CAML interactor-immunoglobulin; Recombinant TACI-Fc; B-cell inhibitor; TACI-Fc fusion protein; APRIL/BLyS inhibitor; RG-3647
EINECS	Contact for details

Quality Control

Our Atacicept is produced and tested under stringent quality management systems. Each batch is subjected to a comprehensive suite of analytical tests to ensure identity, purity, potency, and safety, meeting high standards for research-grade biologics. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (SDS-PAGE)	≥ 95%
Purity (SEC-HPLC)	≥ 98.0% (Monomer)
Assay (Protein Content)	≥ 95% of label claim
Endotoxin	< 1.0 EU/mg
Biological Activity (Cell-based assay)	Contact for details
Residual Moisture (KF)	< 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.