Description

3-Oxo-2-Pyridin-4-Ylmethyl-2,3-Dihydro-1H-Isoindole-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex isoindole and pyridine-containing molecular frameworks.
• Research & Development (R&D): Essential for academic and industrial laboratories exploring new heterocyclic compounds and their biological activities.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing routes.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) supporting global drug development pipelines.

Basic Information

Product Name	3-Oxo-2-Pyridin-4-Ylmethyl-2,3-Dihydro-1H-Isoindole-4-Carboxylic Acid
CAS No.	842974-44-1
Molecular Formula	C16H12N2O3
Molecular Weight	280.28 g/mol
Synonyms	4-Carboxy-2-(4-pyridylmethyl)isoindolin-1-one; 1H-Isoindole-4-carboxylic acid, 2,3-dihydro-3-oxo-2-(4-pyridinylmethyl)-; 2-(Pyridin-4-ylmethyl)-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid; 842974-44-1; 3-Oxo-2-(4-pyridinylmethyl)-2,3-dihydro-1H-isoindole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Oxo-2-Pyridin-4-Ylmethyl-2,3-Dihydro-1H-Isoindole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is compatible with strong acid/organic solvent environments but should be kept separate from incompatible materials. For long-term storage, consider under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.