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tert-Butyl 4-(7-Bromo-4-Chloro-1-Ethyl-1H-Imidazo[4,5-C]Pyridin-2-Yl)-1,2,5-Oxadiazol-3-Ylcarbamate CAS NO 842144-08-5
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CAS No.:842144-08-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
tert-Butyl 4-(7-Bromo-4-Chloro-1-Ethyl-1H-Imidazo[4,5-C]Pyridin-2-Yl)-1,2,5-Oxadiazol-3-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel drug candidates, especially in oncology and immunology.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of novel, potent kinase inhibitors and other biologically active molecules.
- Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
- Preclinical Development: Serves as a critical precursor for producing compounds for in vitro and in vivo biological testing.
- Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
- Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
- Chemical Reference Standard: Can be used as a high-purity analytical standard for quality control and method development.
Basic Information
| Product Name | tert-Butyl 4-(7-Bromo-4-Chloro-1-Ethyl-1H-Imidazo[4,5-C]Pyridin-2-Yl)-1,2,5-Oxadiazol-3-Ylcarbamate |
| CAS No. | 842144-08-5 |
| Molecular Formula | C15H16BrClN6O3 |
| Molecular Weight | 443.69 g/mol |
| Synonyms | tert-Butyl (4-(7-bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-yl)carbamate; 1,2,5-Oxadiazol-3-carboxamide, N-(1,1-dimethylethyl)-4-(7-bromo-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-; 842144-08-5; BOC-protected imidazopyridine oxadiazole; 7-Bromo-4-chloro-1-ethyl-2-(3-((tert-butoxycarbonyl)amino)-1,2,5-oxadiazol-4-yl)-1H-imidazo[4,5-c]pyridine |
| EINECS | Contact for details |
Quality Control
Our tert-Butyl 4-(7-Bromo-4-Chloro-1-Ethyl-1H-Imidazo[4,5-C]Pyridin-2-Yl)-1,2,5-Oxadiazol-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
| Single Unknown Impurity (HPLC) | ≤ 1.0% |
| Total Impurities (HPLC) | ≤ 3.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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