Description

tert-Butyl4-(3-(n-Hydroxycarbamimidoyl)Pyridin-2-Yl)Piperazine-1-Carboxylate CAS NO 840454-87-7 is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly as a key building block for targeted inhibitors. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules. The material's specific functional groups make it a versatile precursor for further chemical elaboration.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• HDAC Inhibitor Precursor: Acts as a key synthon in the development of histone deacetylase (HDAC) inhibitors, a class of compounds with applications in oncology and neurology.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and drug discovery.

Basic Information

Product Name	tert-Butyl4-(3-(n-Hydroxycarbamimidoyl)Pyridin-2-Yl)Piperazine-1-Carboxylate
CAS No.	840454-87-7
Molecular Formula	C15H23N5O3
Molecular Weight	321.38 g/mol
Synonyms	tert-Butyl 4-[3-(N-hydroxycarbamimidoyl)pyridin-2-yl]piperazine-1-carboxylate; 1-Boc-4-[3-(N-hydroxyamidino)-2-pyridyl]piperazine; 840454-87-7; tert-Butyl 4-(3-(N-hydroxycarbamimidoyl)pyridin-2-yl)piperazine-1-carboxylate; 2-Pyridinecarboximidamide, N-hydroxy-, 2-(4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl)-; 1-Piperazinecarboxylic acid, 4-[3-[(hydroxyamino)iminomethyl]-2-pyridinyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl4-(3-(n-Hydroxycarbamimidoyl)Pyridin-2-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring material suitable for advanced research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.