Description

7-Methyl-4-Oxo-2-(4-Phenyl-Piperazin-1-Yl)-4H-Pyrido[1,2-A]Pyrimidine-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused pyrimidine-piperazine structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents targeting central nervous system and other disorders. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies and hit-to-lead optimization campaigns.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) against various biological targets.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for candidate drugs.
• Biochemical Tool Compound: May be used in biochemical assays to study specific enzyme inhibition or receptor modulation.
• Academic Research: Applied in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	7-Methyl-4-Oxo-2-(4-Phenyl-Piperazin-1-Yl)-4H-Pyrido[1,2-A]Pyrimidine-3-Carbaldehyde
CAS No.	839680-02-3
Molecular Formula	C20H20N4O2
Molecular Weight	348.40 g/mol
Synonyms	7-Methyl-4-oxo-2-(4-phenylpiperazin-1-yl)-4H-pyrido[1,2-a]pyrimidine-3-carboxaldehyde; 2-(4-Phenyl-1-piperazinyl)-7-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde; 4H-Pyrido[1,2-a]pyrimidine-3-carbaldehyde, 7-methyl-4-oxo-2-(4-phenyl-1-piperazinyl)-; 839680-02-3; 7-Methyl-2-(4-phenylpiperazin-1-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde; Pyrido[1,2-a]pyrimidine-3-carbaldehyde derivative
EINECS	Contact for details

Quality Control

Our 7-Methyl-4-Oxo-2-(4-Phenyl-Piperazin-1-Yl)-4H-Pyrido[1,2-A]Pyrimidine-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support development and cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.