Description

2-{[1-(4-Chlorophenyl)-2,5-Dioxopyrrolidin-3-Yl]Sulfanyl}Pyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolidine-2,5-dione (succinimide) and pyridine carboxylic acid structure. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of novel drug candidates with potential biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Bioconjugation & Probe Development: The reactive succinimide moiety makes it suitable for creating bioconjugates or chemical probes for biological studies.
• Organic Synthesis Building Block: Employed in constructing complex heterocyclic compounds for agrochemical or material science applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	2-{[1-(4-Chlorophenyl)-2,5-Dioxopyrrolidin-3-Yl]Sulfanyl}Pyridine-3-Carboxylic Acid
CAS No.	838890-59-8
Molecular Formula	C16H11ClN2O4S
Molecular Weight	362.79 g/mol
Synonyms	2-({1-[(4-Chlorophenyl)]-2,5-dioxo-3-pyrrolidinyl}sulfanyl)-3-pyridinecarboxylic acid; 2-[[1-(4-Chlorophenyl)-2,5-dioxo-3-pyrrolidinyl]thio]nicotinic acid; 2-{[1-(4-Chlorophenyl)-2,5-dioxo-3-pyrrolidinyl]sulfanyl}nicotinic acid; 838890-59-8; 2-[(1-(4-Chlorophenyl)-2,5-dioxopyrrolidin-3-yl)sulfanyl]pyridine-3-carboxylic acid; Nicotinic acid, 2-[[1-(4-chlorophenyl)-2,5-dioxo-3-pyrrolidinyl]thio]-; 3-Pyridinecarboxylic acid, 2-[[1-(4-chlorophenyl)-2,5-dioxo-3-pyrrolidinyl]thio]-
EINECS	Contact for details

Quality Control

Our 2-{[1-(4-Chlorophenyl)-2,5-Dioxopyrrolidin-3-Yl]Sulfanyl}Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.