Description

Mifamurtide Hydrate is a synthetic lipophilic derivative of muramyl dipeptide, designed as an immunomodulator for targeted therapeutic applications. Its primary commercial value lies in its potent activation of macrophages and monocytes, which is critical for stimulating the body's innate immune response against specific pathological conditions. This product is essential for pharmaceutical R&D and manufacturing, particularly in the development of advanced immunotherapies for oncology and other immune-related disorders. CAS No. 838853-48-8.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active pharmaceutical ingredient in the formulation of immunotherapeutic drugs.
• Oncology Research: Critical component in preclinical and clinical research for developing treatments against osteosarcoma and other cancers.
• Immunology Studies: Used as a research tool to study macrophage activation, cytokine release, and innate immune system pathways.
• Drug Delivery System Development: Incorporated into liposomal or nanoparticle formulations to enhance targeted delivery and efficacy.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.
• Combination Therapy Development: Investigated in conjunction with chemotherapy agents to improve therapeutic outcomes.

Basic Information

Product Name	Mifamurtide Hydrate
CAS No.	838853-48-8
Molecular Formula	C46H78N6O19P2 • xH2O
Molecular Weight	1057.09 g/mol (anhydrous basis)
Synonyms	Mifamurtide; L-MTP-PE; Liposomal MTP-PE; Muramyl Tripeptide Phosphatidylethanolamine; CGP 19835; CGP-19835A; Mepact; Junovan; Liposomal Muramyl Tripeptide
EINECS	Contact for details

Quality Control

Our Mifamurtide Hydrate is manufactured under strict quality systems suitable for pharmaceutical development. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications. A Certificate of Analysis (COA) documenting identity, purity (by HPLC), water content, and related substances is provided with every shipment to guarantee traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, 15-25°C, or as indicated on the label. The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.