Description

5-Pyridin-3-Ylthiophen-2-Amine is a high-purity heterocyclic organic compound featuring a fused pyridine-thiophene core structure. This specialized chemical building block is critical for advanced research and development in medicinal chemistry and material science. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Precursor: Serves as a building block for organic semiconductors, conductive polymers, and advanced organic light-emitting diodes (OLEDs).
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Institutional Research: Used in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.
• Custom Synthesis Starting Material: A foundational compound for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	5-Pyridin-3-Ylthiophen-2-Amine
CAS No.	837376-58-6
Molecular Formula	C9H8N2S
Molecular Weight	176.24 g/mol
Synonyms	3-(2-Aminothiophen-5-yl)pyridine; 5-(3-Pyridinyl)-2-thiophenamine; 2-Amino-5-(pyridin-3-yl)thiophene; 5-(Pyridin-3-yl)thiophen-2-amine; 3-Pyridin-3-ylthiophen-2-ylamine; 5-(3-Pyridyl)thiophen-2-amine
EINECS	Contact for details

Quality Control

Every batch of 5-Pyridin-3-Ylthiophen-2-Amine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade meets a typical purity specification of ≥97% (HPLC), with higher purity grades available. A detailed Certificate of Analysis (COA) providing batch-specific results for all critical parameters is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.