Description

n-Methyl-(5-Pyrid-3-Ylthien-2-Yl)Methylamine is a specialized heterocyclic amine building block featuring a pyridine-thiophene core structure. This compound is of significant value in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic scaffold.
• Ligand Synthesis: Serves as a precursor for creating novel ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science: Investigated for use in the development of organic semiconductors, conductive polymers, and light-emitting materials.
• Chemical Biology: Employed as a probe or tag in biochemical research to study protein interactions and enzyme function.
• Custom Synthesis: Provides a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers for client-specific projects.

Basic Information

Product Name	n-Methyl-(5-Pyrid-3-Ylthien-2-Yl)Methylamine
CAS No.	837376-49-5
Molecular Formula	C11H12N2S
Molecular Weight	204.29 g/mol
Synonyms	1-(5-(Pyridin-3-yl)thiophen-2-yl)-N-methylmethanamine; N-Methyl-1-[5-(3-pyridinyl)-2-thienyl]methanamine; 3-((5-((Methylamino)methyl)thiophen-2-yl)pyridine; (5-(Pyridin-3-yl)thiophen-2-yl)methyl(methyl)amine; 837376-49-5; Building block for kinase inhibitors; Pyridine-thiophene amine derivative
EINECS	Contact for details

Quality Control

Our n-Methyl-(5-Pyrid-3-Ylthien-2-Yl)Methylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and related substances, supporting its use in GLP and cGMP environments for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.