Description

4-(1-((Benzyloxy)Methyl)-5-(Pyridin-4-Yl)-1H-1,2,4-Triazol-3-Yl)Picolinonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in oncology and antiviral research. The product is supplied under stringent quality control to ensure batch-to-batch consistency for sensitive R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Kinase Inhibitor Development: The triazole and pyridine motifs make it a valuable scaffold for developing potential kinase inhibitors.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study enzyme function and cellular processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	4-(1-((Benzyloxy)Methyl)-5-(Pyridin-4-Yl)-1H-1,2,4-Triazol-3-Yl)Picolinonitrile
CAS No.	837371-70-7
Molecular Formula	C21H16N6O
Molecular Weight	368.39 g/mol
Synonyms	4-[1-(Benzyloxymethyl)-5-(4-pyridyl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile; 4-[1-[(Benzyloxy)methyl]-5-(4-pyridinyl)-1H-1,2,4-triazol-3-yl]-2-pyridinecarbonitrile; 837371-70-7; BOT-4-12; 4-(1-(Benzyloxymethyl)-5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl)picolinonitrile; Picolinonitrile, 4-[1-[(benzyloxy)methyl]-5-(4-pyridinyl)-1H-1,2,4-triazol-3-yl]-
EINECS	Contact for details

Quality Control

Our 4-(1-((Benzyloxy)Methyl)-5-(Pyridin-4-Yl)-1H-1,2,4-Triazol-3-Yl)Picolinonitrile is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the high standards required for pharmaceutical research. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can support development with specifications aligned with ICH guidelines for impurities and stability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.