Description

2,6-Difluoro-4-hydrazinyl-pyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both fluorine substituents and a reactive hydrazine group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of fluorine.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	2,6-Difluoro-4-hydrazinyl-pyridine
CAS No.	837364-94-0
Molecular Formula	C5H5F2N3
Molecular Weight	145.11 g/mol
Synonyms	4-Hydrazinyl-2,6-difluoropyridine; 2,6-Difluoropyridine-4-hydrazine; 2,6-Difluoro-4-hydrozinylpyridine; 2,6-Difluoro-4-pyridinylhydrazine; 4-Hydrazino-2,6-difluoropyridine; Pyridine, 2,6-difluoro-4-hydrozinyl-; 837364-94-0 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-hydrazinyl-pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and identity confirmation. Our quality commitment aligns with the standards required for pharmaceutical and agrochemical development, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.