Description

Ethyl 2-Iodo-5-Nitrobenzoate is a high-purity, multi-functional organic building block characterized by its distinct iodo and nitro substituents on the benzoate core. This compound is essential for facilitating advanced synthetic transformations, particularly in the construction of complex heterocyclic and pharmaceutical intermediates. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in cross-coupling reactions, nucleophilic aromatic substitution, and as a precursor in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, leveraging its reactivity in palladium-catalyzed cross-couplings like Suzuki, Stille, and Sonogashira reactions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the nitro and iodo groups allow for strategic functionalization of lead structures.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a tagging or labeling reagent for biomolecules due to the photoreactive or coupling potential of its functional groups.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis studies within university and corporate research laboratories.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex aromatic structures for specialized dyes and functional pigments.

Basic Information

Product Name	Ethyl 2-Iodo-5-Nitrobenzoate
CAS No.	835916-53-5
Molecular Formula	C9H8INO4
Molecular Weight	321.07 g/mol
Synonyms	Benzoic acid, 2-iodo-5-nitro-, ethyl ester; Ethyl 2-iodo-5-nitrobenzoate; 2-Iodo-5-nitrobenzoic acid ethyl ester; Ethyl o-iodo-5-nitrobenzoate; 5-Nitro-2-iodobenzoic acid ethyl ester; Ethyl 5-nitro-2-iodobenzoate; Iodo-nitrobenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Iodo-5-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material is suitable for demanding applications in research and scale-up environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.