Description

Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, Propyl Ester, (1S,2S)- (9Ci) is a high-purity, stereochemically defined chiral building block. This compound matters for its role as a critical intermediate in the synthesis of complex, biologically active molecules, offering precise control over the final product's stereochemistry. It is primarily needed by pharmaceutical R&D and process chemistry teams for developing advanced active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Agrochemical Research: Serves as a precursor in the development of new, more effective pesticides and herbicides with specific chiral activity.
• Ligand and Catalyst Development: Used in the preparation of specialized chiral ligands and organocatalysts for catalytic asymmetric transformations.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals where stereochemical integrity is paramount.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process optimization in pilot-scale facilities.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, Propyl Ester, (1S,2S)- (9Ci)
CAS No.	834886-29-2
Molecular Formula	C10H15NO3
Molecular Weight	197.23 g/mol
Synonyms	(1S,2S)-2-Cyano-2-hydroxycyclopentanecarboxylic acid propyl ester; (1S,2S)-2-Hydroxy-2-cyanocyclopentanecarboxylic acid propyl ester; Propyl (1S,2S)-2-cyano-2-hydroxycyclopentanecarboxylate; (1S,2S)-CHCPE; (1S,2S)-2-Cyano-2-hydroxycyclopentane-1-carboxylic acid propyl ester
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, Propyl Ester, (1S,2S)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the exacting standards required for pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly sealed due to potential sensitivity to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.