Description

Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, 1-Methylethyl Ester, (1S,2R)- (9Ci) is a high-purity, chiral organic compound with the CAS number 834886-12-3. This molecule serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in asymmetric synthesis. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of complex, optically active target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or metabolic diseases.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Agrochemical Research: Serves as a precursor in the development of novel, chiral pesticides and herbicides where specific stereochemistry is crucial for bioactivity.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers with unique optical or mechanical properties.
• Academic & Contract Research: Used in university and CRO laboratories for methodological development in organic chemistry and catalysis studies.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, 1-Methylethyl Ester, (1S,2R)- (9Ci)
CAS No.	834886-12-3
Molecular Formula	C10H15NO3
Molecular Weight	197.23 g/mol
Synonyms	(1S,2R)-2-Cyano-2-hydroxycyclopentanecarboxylic acid 1-methylethyl ester; (1S,2R)-Isopropyl 2-cyano-2-hydroxycyclopentanecarboxylate; (1S,2R)-2-Hydroxy-2-cyanocyclopentanecarboxylic acid isopropyl ester; (1S,2R)-rel-2-Cyano-2-hydroxycyclopentanecarboxylic acid 1-methylethyl ester; Isopropyl (1S,2R)-2-cyano-2-hydroxycyclopentane-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, 1-Methylethyl Ester, (1S,2R)- (9Ci) adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); therefore, it is recommended to handle under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.