Description

Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, Propyl Ester, (1S,2R)- (9Ci) is a high-purity, stereochemically defined chiral building block. This compound matters for its role as a critical intermediate in the synthesis of complex, biologically active molecules, offering precise control over stereochemistry. It is primarily needed by pharmaceutical R&D and process chemistry teams for the development of new active pharmaceutical ingredients (APIs) and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Agrochemical Research: Serves as a building block for developing advanced, chiral active ingredients with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Used in the preparation of novel chiral ligands and organocatalysts for catalytic asymmetric transformations.
• Academic & Industrial R&D: Employed in chemical biology and medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, Propyl Ester, (1S,2R)- (9Ci)
CAS No.	834886-11-2
Molecular Formula	C10H15NO3
Molecular Weight	197.23 g/mol
Synonyms	(1S,2R)-2-Cyano-2-hydroxycyclopentanecarboxylic acid propyl ester; Propyl (1S,2R)-2-cyano-2-hydroxycyclopentanecarboxylate; (1S,2R)-2-Hydroxy-2-cyanocyclopentanecarboxylic acid propyl ester; (1S,2R)-rel-2-Cyano-2-hydroxycyclopentanecarboxylic Acid Propyl Ester; Cyclopentanecarboxylic acid, 2-cyano-2-hydroxy-, propyl ester, (1S,2R)-rel-; (1S,2R)-2-Cyano-2-hydroxy-cyclopentanecarboxylic acid propyl ester
EINECS	Contact for details

Quality Control

Every batch of Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, Propyl Ester, (1S,2R)- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for pharmaceutical research, including confirmation of stereochemical purity. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.