Description

Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, 1-Methylethyl Ester, (1R,2R)-Rel- (9Ci) is a high-value, stereochemically defined chiral intermediate essential for the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. Its precise (1R,2R)-relative configuration makes it a critical building block for constructing molecules with specific three-dimensional architectures required for optimal biological activity. This compound is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex cyclic structures.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where stereochemistry impacts efficacy and environmental profile.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new stereoselective catalytic reactions.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for producing specialty chemicals with high added value.
• Academic & Industrial R&D: A tool compound for methodological studies in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, 1-Methylethyl Ester, (1R,2R)-Rel- (9Ci)
CAS No.	834885-93-7
Molecular Formula	C10H15NO3
Molecular Weight	197.23 g/mol
Synonyms	rel-(1R,2R)-2-Cyano-2-hydroxycyclopentanecarboxylic acid 1-methylethyl ester; Isopropyl (1R,2R)-rel-2-cyano-2-hydroxycyclopentanecarboxylate; (1R,2R)-rel-2-Hydroxy-2-cyanocyclopentanecarboxylic acid isopropyl ester; 2-Cyano-2-hydroxycyclopentanecarboxylic acid isopropyl ester, (1R,2R)-rel-; Isopropyl 2-cyano-2-hydroxycyclopentanecarboxylate (relative configuration); Chiral cyano-hydroxycyclopentane ester
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency critical for process development and scale-up. Identity, purity, and stereochemical integrity are verified using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (for specified diastereomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.