Description

Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, 1-Methylethyl Ester, (1R,2S)-Rel- (9Ci) CAS NO 834885-87-9 is a high-purity, chiral organic intermediate of significant importance in advanced synthetic chemistry. This compound is valued for its stereochemically defined structure, which is critical for imparting specific biological activity and selectivity in final target molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly in therapeutic areas requiring high stereochemical purity.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to construct molecules with defined three-dimensional architecture.
• Agrochemical Research: Serves as a starting material for developing novel, stereoselective pesticides and herbicides.
• Material Science: Potential monomer or additive for creating specialized polymers with unique optical or mechanical properties.
• Academic & Contract Research: Essential for methodological development in organic chemistry and for custom synthesis projects in CRO/CMO settings.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, 1-Methylethyl Ester, (1R,2S)-Rel- (9Ci)
CAS No.	834885-87-9
Molecular Formula	C10H15NO3
Molecular Weight	197.23 g/mol
Synonyms	(1R,2S)-rel-2-Hydroxy-2-cyanocyclopentanecarboxylic acid 1-methylethyl ester; Isopropyl (1R,2S)-rel-2-cyano-2-hydroxycyclopentanecarboxylate; (1R,2S)-rel-Isopropyl 2-cyano-2-hydroxycyclopentanecarboxylate; 2-Cyano-2-hydroxycyclopentanecarboxylic acid isopropyl ester, (1R,2S)-rel-; (1R,2S)-rel-2-Hydroxy-2-cyanocyclopentane-1-carboxylic acid isopropyl ester
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Every lot is characterized using advanced analytical techniques including HPLC, GC, and chiral analysis to confirm identity, potency, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong alkalis and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.