Description

Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, Propyl Ester, (1R,2S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly in the pharmaceutical sector. It is primarily needed by R&D chemists and process development scientists in pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures with precise stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in projects targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Research: Used in the development of new, stereoselective herbicides, fungicides, or plant growth regulators where the specific spatial orientation of the molecule is crucial for activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands used in asymmetric hydrogenation or other enantioselective transformations.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic compounds for research and development.
• Academic & Institutional Research: A valuable tool in university and institutional labs for methodological studies in stereoselective synthesis and natural product synthesis.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, Propyl Ester, (1R,2S)-Rel- (9Ci)
CAS No.	834885-86-8
Molecular Formula	C10H15NO3
Molecular Weight	197.23 g/mol
Synonyms	(1R,2S)-rel-2-Cyano-2-hydroxycyclopentanecarboxylic acid propyl ester; Propyl (1R,2S)-rel-2-cyano-2-hydroxycyclopentanecarboxylate; rel-(1R,2S)-2-Hydroxy-2-cyanocyclopentanecarboxylic acid propyl ester; 2-Cyano-2-hydroxycyclopentanecarboxylic acid propyl ester, (1R,2S)-rel-; (1R,2S)-rel-2-Hydroxy-2-cyanocyclopentanecarboxylic Acid Propyl Ester; Cyclopentanecarboxylic acid, 2-cyano-2-hydroxy-, propyl ester, (1R,2S)-rel-; Chiral cyano-hydroxy cyclopentane ester
EINECS	Contact for details

Quality Control

Our high-value chiral intermediates are produced under strict quality control protocols to ensure batch-to-batch consistency and stereochemical integrity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and MS to confirm identity, enantiomeric/excess, and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our manufacturing aligns with cGMP principles where applicable, supporting our clients' regulatory filing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.