Description

(4-Bromophenyl)(4-Boc-1,4-Diazepan-1-Yl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique diazepane scaffold protected by a Boc (tert-butoxycarbonyl) group. This compound is specifically engineered for the synthesis of complex bioactive molecules, offering a critical building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting GPCRs (G-protein-coupled receptors).
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing libraries of compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• API (Active Pharmaceutical Ingredient) Development: Used in the development and scale-up stages of new active pharmaceutical ingredients requiring a functionalized diazepane moiety.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Item	Detail
Product Name	(4-Bromophenyl)(4-Boc-1,4-Diazepan-1-Yl)Acetic Acid
CAS No.	834884-94-5
Molecular Formula	C19H27BrN2O4
Molecular Weight	427.34 g/mol
Synonyms	1-(4-Bromophenyl)-1-oxo-2-[4-(tert-butoxycarbonyl)-1,4-diazepan-1-yl]ethane; 2-(4-Boc-1,4-diazepan-1-yl)-2-(4-bromophenyl)acetic acid; 4-Boc-1,4-diazepane-1-acetic acid, 4-bromophenyl derivative; (4-Bromophenyl)(4-(tert-butoxycarbonyl)-1,4-diazepan-1-yl)acetic acid; 1,4-Diazepane-1-acetic acid, 4-(1,1-dimethylethoxy)carbonyl-, 4-bromophenyl ester (related); Boc-1,4-diazepane acetic acid bromophenyl derivative
EINECS	Contact for details

Quality Control

Our (4-Bromophenyl)(4-Boc-1,4-Diazepan-1-Yl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled in a strong acid/organic solvent environment. Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.