Description

[4-(6-Formylpyridin-2-Yl)Phenyl]Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique pyridine-formyl-phenyl carbamate structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel kinase inhibitors and other small-molecule drug candidates.
• Chemical Research & Development: Serves as a versatile building block for constructing complex heterocyclic frameworks in medicinal chemistry programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the final stages or penultimate steps of API manufacturing processes for targeted therapies.
• Bioconjugation & Probe Development: The formyl group enables site-specific conjugation, useful for creating fluorescent probes or antibody-drug conjugates (ADCs) for diagnostic and therapeutic applications.
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	[4-(6-Formylpyridin-2-Yl)Phenyl]Carbamic Acid tert-Butyl Ester
CAS No.	834884-86-5
Molecular Formula	C17H18N2O3
Molecular Weight	298.34 g/mol
Synonyms	tert-Butyl N-[4-(6-formyl-2-pyridinyl)phenyl]carbamate; 4-(6-Formylpyridin-2-yl)phenylcarbamic Acid tert-Butyl Ester; BOC-4-(6-Formylpyridin-2-yl)aniline; N-Boc-4-(6-formylpyridin-2-yl)aniline; 2-(4-((tert-Butoxycarbonyl)amino)phenyl)picolinaldehyde; 834884-86-5; Carbamic acid, N-[4-(6-formyl-2-pyridinyl)phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of [4-(6-Formylpyridin-2-Yl)Phenyl]Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for pharmaceutical R&D and cGMP starting material applications. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥95% by HPLC), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.