Description

(R)-Methyl-(5,6,7,8-Tetrahydro-Quinolin-8-Yl)-Amine is a chiral amine derivative of tetrahydroquinoline, serving as a high-value pharmaceutical intermediate and chiral building block. This compound matters for its role in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), where its specific stereochemistry is critical for biological activity and drug efficacy. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors engaged in developing novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiopure drugs, particularly in central nervous system (CNS) and oncology research.
• Asymmetric Catalyst Ligand: Used as a precursor or ligand in asymmetric catalysis to induce chirality in synthetic reactions.
• Agrochemical Synthesis: Employed in the development of advanced, stereospecific pesticides and herbicides.
• Fine Chemical Building Block: Serves as a versatile intermediate for constructing complex nitrogen-containing heterocycles in academic and industrial R&D.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and target identification.

Basic Information

Product Name	(R)-Methyl-(5,6,7,8-Tetrahydro-Quinolin-8-Yl)-Amine
CAS No.	834884-60-5
Molecular Formula	C11H16N2
Molecular Weight	176.26 g/mol
Synonyms	(R)-8-(Methylamino)-5,6,7,8-tetrahydroquinoline; (R)-N-Methyl-1,2,3,4-tetrahydroquinolin-8-amine; (8R)-N-Methyl-5,6,7,8-tetrahydroquinolin-8-amine; (R)-N-Methyl-5,6,7,8-tetrahydroquinolin-8-amine; (R)-MTAQ; (R)-Methyltetrahydroquinolinylamine
EINECS	Contact for details

Quality Control

Our (R)-Methyl-(5,6,7,8-Tetrahydro-Quinolin-8-Yl)-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.