Description

Carbamic Acid tert-Butyl Ester is a specialized organic compound serving as a versatile building block and protecting group in advanced synthetic chemistry. Its primary value lies in its role as a key intermediate for the synthesis of pharmaceuticals, agrochemicals, and complex organic molecules. This high-purity intermediate is essential for research and development laboratories, as well as production facilities in the pharmaceutical and fine chemical industries, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring tert-butoxycarbonyl (Boc) protection of amines.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and plant growth regulators.
• Peptide Chemistry: Serves as a Boc-protecting agent for amino groups during solid-phase and solution-phase peptide synthesis, preventing unwanted side reactions.
• Organic Synthesis Reagent: Employed in multi-step organic synthesis for introducing the carbamate or tert-butyloxycarbonyl functional group into target molecules.
• Research & Development: A valuable tool for medicinal chemists and researchers in academia and industry exploring new chemical entities and reaction pathways.
• Fine Chemical Production: Used in the manufacture of dyes, flavors, fragrances, and other specialty chemicals requiring high-purity intermediates.

Basic Information

Product Name	Carbamic Acid tert-Butyl Ester
CAS No.	834868-97-2
Molecular Formula	C5H11NO2
Molecular Weight	117.15 g/mol
Synonyms	tert-Butyl carbamate; N-Boc-amine; Boc-NH2; (tert-Butoxy)formamide; Carbamic acid, 1,1-dimethylethyl ester; 2-Methyl-2-propanyl carbamate; BOC-Amine; N-(tert-Butoxycarbonyl)amine
EINECS	Contact for details

Quality Control

Our Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	85 - 89 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.